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Table 2 Serum adenosine deaminase and interferon-γ levels in patients with tuberculosis, malignancy and non-tuberculosis non-malignancy in the study group

From: Diagnostic utility of serum and pleural levels of adenosine deaminase 1–2, and interferon-γ in the diagnosis of pleural tuberculosis

 

Group 1 (Tuberculosis) (n = 23)

Group 2 (Malignancy) (n = 11)

Group 3 (Non-tuberculosis non-malignancy) (n = 18)

p Value

Age (yrs)

25 (20–37)

65 (50–68)

67.5 (45–75)

0.0001

P (1–2) = 0.0001

P (1–3) = 0.0001

P (2–3) = 0.946

Male/female

15/8

7/4

15/3

0.368

Serum ADA-1 (U/L)

11.32 (4.43-18.01)

11.52 (8.64-16.24)

10.81 (6.70-14.89)

0.983

Serum ADA-2 (U/L)

16.54 (12.11-20.77)

11.36 (7.16-20.00)

10.00 (6.59-13.00)

0.004

P (1–2) = 0.068

P (1–3) = 0.001

P (2–3) = 0.393

Serum total ADA (U/L)

28.98 (24.51-33.66)

27.39 (15.68-35.14)

21.70 (17.73-27.05)

0.034

P (1–2) = 0.473

P (1–3) = 0.004

P (2–3) = 0.605

Serum μg/ml (pg/ml)

75.00 (35.00-160.00)

50.00 (15.00-90.00)

57.50 (30.00-115.00)

0.513

  1. ADA, Adenosine deaminase; IFN-γ, Interferon gamma.
  2. Data are expressed as median (interquartile range).