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Table 2 Serum adenosine deaminase and interferon-γ levels in patients with tuberculosis, malignancy and non-tuberculosis non-malignancy in the study group

From: Diagnostic utility of serum and pleural levels of adenosine deaminase 1–2, and interferon-γ in the diagnosis of pleural tuberculosis

  Group 1 (Tuberculosis) (n = 23) Group 2 (Malignancy) (n = 11) Group 3 (Non-tuberculosis non-malignancy) (n = 18) p Value
Age (yrs) 25 (20–37) 65 (50–68) 67.5 (45–75) 0.0001 P (1–2) = 0.0001
P (1–3) = 0.0001
P (2–3) = 0.946
Male/female 15/8 7/4 15/3 0.368
Serum ADA-1 (U/L) 11.32 (4.43-18.01) 11.52 (8.64-16.24) 10.81 (6.70-14.89) 0.983
Serum ADA-2 (U/L) 16.54 (12.11-20.77) 11.36 (7.16-20.00) 10.00 (6.59-13.00) 0.004 P (1–2) = 0.068
P (1–3) = 0.001
P (2–3) = 0.393
Serum total ADA (U/L) 28.98 (24.51-33.66) 27.39 (15.68-35.14) 21.70 (17.73-27.05) 0.034 P (1–2) = 0.473
P (1–3) = 0.004
P (2–3) = 0.605
Serum μg/ml (pg/ml) 75.00 (35.00-160.00) 50.00 (15.00-90.00) 57.50 (30.00-115.00) 0.513
  1. ADA, Adenosine deaminase; IFN-γ, Interferon gamma.
  2. Data are expressed as median (interquartile range).