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Table 1 Clinical and metabolic parameters (mean ± SD)

From: Acid–base balance, serum electrolytes and need for non-invasive ventilation in patients with hypercapnic acute exacerbation of chronic obstructive pulmonary disease admitted to an internal medicine ward

Variables

NIV- (N = 55)

NIV+ (N = 55)

p

Age (years)

77.5 ± 8.8

77.6 ± 10.7

0.94

Gender (M/F)

29/26

28/27

0.85

Glucose (mg/dl)

142.3 ± 48.9

156.2 ± 76.5

0.26

Serum Uric Acid (mg/dl)

6.3 ± 2.0

6.6 ± 2.6

0.60

Serum Albumin (g/dl)

3.3 ± 0.5

2.9 ± 0.5

<0.001

C-Reactive-Protein (mg/l)

76.9 ± 75.7

27.4 ± 34.4

0.039

Serum Creatinine (mg/dl)

1.08 ± 0.58

1.29 ± 0.88

0.14

GFR (MDRD ml/min/1.73 m2)

71.8 ± 32.0

72.7 ± 49.3

0.91

HR (bpm)

83.8 ± 12.7

93.6 ± 13.6

<0.001

SBP (mmHg)

124.1 ± 17.0

120.0 ± 17.9

0.21

DBP (mmHg)

74.2 ± 9.9

72.5 ± 10.2

0.38

PaO2 (mmHg)

58.4 ± 13.5

60.2 ± 16.2

0.54

PaO2/FiO2

255.9 ± 38.6

200.2 ± 57.6

<0.001

pH

7.42 ± 0.05

7.29 ± 0.11

<0.001

PaCO2 (mmHg)

50.5 ± 5.5

75.5 ± 19.8

<0.001

Lactate (mmol/L)

1.38 ± 0.68

2.01 ± 1.76

0.017

Serum HCO3 (mmol/L)

32.6 ± 5.5

36.0 ± 10.1

0.036

Serum Na+ (mmol/L)

138.6 ± 3.9

139.1 ± 6.9

0.63

Serum K+ (mmol/L)

4.4 ± 0.6

4.7 ± 0.8

0.037

Serum Ca++ (mmol/L)

8.6 ± 0.6

8.4 ± 0.8

0.12

Serum Mg+ (mmol/L)

1.96 ± 0.32

1.89 ± 0.32

0.24

Serum Cl (mmol/L)

99.4 ± 3.9

96.6 ± 8.1

0.030

  1. GFR Glomerular Filtration Rate, MDRD Modification of Diet in Renal Disease