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Fig. 2 | Multidisciplinary Respiratory Medicine

Fig. 2

From: Efficacy of recombinant human soluble thrombomodulin for the treatment of acute exacerbation of idiopathic pulmonary fibrosis: a single arm, non-randomized prospective clinical trial

Fig. 2

Serial changes in coagulation markers and HMGB1 levels of the patients in the rhTM group (n = 10). There were no significant changes between the serial change in D-dimer, TAT, PIC and HMGB1 (one-way repeated ANOVA). Data are expressed as the group means ± standard deviation. HMGB1: high mobility group box 1; TAT: thrombin-antithrombin complex; PIC: plasmin-α2 plasmin inhibitor complex. *n = 7, †n = 5

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