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Table 3 ICD-9-CM codes used for identifying comorbidities

From: Pulmonary arterial hypertension associated with interferon therapy: a population-based study

Comorbidity

ICD-9-CM

Connective tissue disorder

446, 701.0, 710.0, 710.1, 710.2, 710.3, 710.4, 710.8, 710.9, 711.2, 714, 719.3, 720, 725, 728.5, 728.89, 729.30

Other liver disease

070.22, 070.23, 070.32, 070.33, 070.6, 070.9, 456.0, 456.1, 456.2, 570, 571, 572.2, 572.3, 572.4, 572.8, 573.3, 573.4, 573.8, 573.9, V42.7

HIV/AIDS

042, 043, 044

Obesity

278.0

Hypertension

401, 402, 403, 404, 405

Congestive heart failure

398.91, 402.01, 402.11, 402.91, 404.01, 404.03, 404.11, 404.13, 404.91, 404.93, 425.4, 425.5, 425.7, 425.8, 425.9, 428

Valvular disease

093.2, 394, 395, 396, 397, 424, 746.3, 746.4, 746.5, 746.6, V42.2, V43.3

Chronic pulmonary disease

416.9, 490, 491, 492, 493, 494, 495, 496, 500, 501, 502, 503, 504, 505, 506.4, 508.1, 508.8

Diabetes

250.0, 250.1, 250.2, 250.3, 250.4, 250.5, 250.6, 250.7, 250.8, 250.9

Congenital heart disease

746.9, 745.4

Atrial fibrillation and flutter

427.3

Sleep apnea

327.21, 327.23, 327.27, 780.51, 780.53, 780.57, 786.03, 786.04

  1. For each of the comorbidities, the study subjects needed to have 2 claims separated by at least 30 days in the year before the interferon initiation to be considered to have that comorbidity