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Table 1 Baseline anthropometric characteristics of study population

From: Using PaCO2 values to grade obesity-hypoventilation syndrome severity: a retrospective study

 

Mild OHSa (n = 46)

Moderate OHSb (n = 24)

Severe OHSc (n = 14)

Age, yrs

55 ± 9.3

52.2 ± 11.1

55.7 ± 6.8

Sex, male/female

33/13

19/5

10/4

BMI, kg/m2

41.5 ± 8.2

45.1 ± 7.3

48.7 ± 6.5#

ESS

11.7 ± 5

13.7 ± 5.8

14.5 ± 4.5

pH

7.40 ± 0.03

7.39 ± 0.04

7.39 ± 0.02

PaO2, mmHg

72.6 ± 6.8

66.2 ± 6.5*

58 ± 6.2**§

PaCO2, mmHg

46.8 ± 1

52.3 ± 1.1*

57.6 ± 1.8**§

HCO3-, mmol/L

29.4 ± 1.7

33.4 ± 2.4*

36.8 ± 2**§

FEV1, % predicted

83.7 ± 15.3

76.4 ± 16.3

71.4 ± 11.5#

FVC, % predicted

85.1 ± 13.9

78.8 ± 15.6

73.9 ± 10.9#

FEV1/FVC ratio, %

80.4 ± 6.7

80 ± 4.1

79.4 ± 4

TLC, % predicted

90 ± 11.6

87.2 ± 16.2

82.9 ± 12.1

Hypertension, n (%)

35 (76)

19 (79)

11 (78)

Diabetes mellitus, n (%)

16 (34)

11 (45)

8 (57)

Dyslipidemia, n (%)

13 (28)

8 (33)

6 (42)

Current smokers, n (%)

11 (23)

10 (41)

4 (28)

Ex smokers, n (%)

19 (41)

4 (16)

5 (35)

  1. Data are presented as mean values ± SD unless otherwise indicated
  2. OHS Obesity-Hypoventilation Syndrome, BMI body mass index, ESS Epworth Sleepiness Scale, FEV 1 forced expiratory volume in 1 s, FVC forced vital capacity, TLC total lung capacity
  3. # P < 0.05 severe vs mild OHS; *P < 0.01 moderate vs mild OHS; **P < 0.01 severe vs moderate OHS; § P < 0.01 severe vs mild OHS
  4. a46 mmHg ≤ PaCO2 ≤ 50 mmHg
  5. b51 mmHg ≤ PaCO2 ≤ 55 mmHg
  6. cPaCO2 ≥ 56 mmHg