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Table 14 Bronchodilators for the treatment of COPD

From: The AIMAR recommendations for early diagnosis of chronic obstructive respiratory disease based on the WHO/GARD model*

Class Drug Characteristics
Long-acting anticholinergics (LAMAs) Tiotropium Length of action 24 hours
Glycopyrronium Length of action 24 hours
Aclidinium Length of action 12 hours
Long-acting beta-2-agonists (LABAs) Formoterol Length of action 12 hours
Salmeterol Length of action 12 hours
Indacaterol Length of action 24 hours
Fixed inhaled corticosteroid (ICS)/ LABA combinations Salmeterol + fluticasone Length of action 12 hours
Formoterol + budesonide Length of action 12 hours
Formoterol + fluticasone Length of action 12 hours
Phosphodiesterase-4 inhibitors Roflumilast Oral - Length of action 24 hours
Other bronchodilator drugs
Short-acting beta-2-agonists (SABAs) Salbutamol, terbutaline, fenoterol Rapid onsetof action. Length of action 4-6 hours
Short-acting anticholinergics(SABAs) Ipratropium and oxitropium bromide Rapid onset but slower than SABAs.
  Length of action 6-8 hours
Methylxanthines Slow-release oral theophylline